Regulation of cell gRowth, death, and polaRization by ERBB4
نویسندگان
چکیده
4 Ville Veikkolainen Regulation of cell growth, death, and polarization by ERBB4 Department of Medical Biochemistry and Genetics, MediCity Research Laboratory, University of Turku, and Turku Graduate School of Biomedical Sciences (TuBS), Turku, Finland Annales Universitatis Turkuensis, Painosalama Oy, Turku Finland 2011
منابع مشابه
Cell Death or Survival Promoted by Alternative Isoforms of ErbB4
The significance of ErbB4 in tumor biology is poorly understood. The ERBB4 gene is alternatively spliced producing juxtamembrane (JM-a and JM-b) and cytoplasmic (CYT-1 and CYT-2) isoforms. Here, signaling via the two alternative ErbB4 JM isoforms (JM-a CYT-2 and JM-b CYT-2) was compared. Fibroblasts expressing ErbB4 JM-a demonstrated enhanced ErbB4 autophosphorylation, growth, and survival. In ...
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